Copper Tripeptide-34
Amino Acid Sequence: Ala-His-Lys.Cu2+
If this name sounds familiar, you're correct. I've previously reviewed COPPER TRIPEPTIDE-1. The only difference between the two is a single amino acid variation. Copper Tripeptide-34 has the AHK sequence, whereas COPPER TRIPEPTIDE-1 has the GHK copper peptide sequence.
But whether it's COPPER TRIPEPTIDE-1 or Copper Tripeptide-34, they both belong to the copper peptide complex series. When it comes to materials in this series, they all offer powerful effects.
In the morphogenesis and growth of hair follicles, dermal papilla cells (DPC) play a crucial role. In 2007, South Korean scientists published a study suggesting that copper tripeptide complexes could act as growth factors for differentiated cells. By stimulating the proliferation of DPC, they enhance the production of vascular endothelial growth factor.
The research further discovered that extremely low concentrations of Copper Tripeptide-34 in vitro can stimulate the elongation of human hair follicles. Moreover, it can significantly reduce the levels of cleaved forms of caspase-3 and PARP.
Acetyl tetrapeptide-3
Amino Acid Sequence: N-Acetyl-L-lysylglycyl-L-histidyl-L-lysinamide
The mechanism of action is quite simple: Acetyl tetrapeptide-3 stimulates dermal cells to accelerate the production of extracellular matrix, particularly laminin, type I, and type III collagens. As mentioned earlier, these are nutrients provided to the growth phase of hair and hair follicles.
Acetyl tetrapeptide-3 has a certain effect on hormone-related hair loss induced by DHT and eyelash growth, making it a promising ingredient.
For example, in 2020, researchers conducted a randomized controlled trial on hair growth using a combination of Acetyl tetrapeptide-3 and TRIFOLIUM PRATENSE (CLOVER) FLOWER EXTRACT (CAPIXYL™, sourced from IFF) alongside 3% minoxidil.
The comparative results after 6 months were quite promising. Whether on men or women, CAPIXYL™ achieved hair growth results comparable to minoxidil.
Scientists at IFF believe that Acetyl tetrapeptide-3 not only maintains the activity of hair follicle stem cells (HFSC) but also regulates the synthesis of DHT by partially inhibiting 5-α reductase activity. Therefore, it can stimulate the process of follicular regeneration and reduce the process of follicular miniaturization.
Myristoyl Pentapeptide-17
Amino Acid Sequence: Myr-Lys-Leu-Ala-Lys-Lys-NH2
Approximately 90% of the components in eyelashes are keratin, which can be considered the core of the core. Research indicates that even applying Myristoyl Pentapeptide-17 at concentrations as low as 10 ppm in vitro (sourced from Symrise as Sympeptide) can significantly increase the expression of various keratin genes and enhance keratin synthesis.
Moreover, compared to the control group, whether over 45 days or 90 days, the use of Myristoyl Pentapeptide-17 can significantly reduce the dormant phase of the eyelash lifecycle, thereby promoting eyelash growth.
Clinical trials conducted on 15 volunteers of varying ages (24-82 years) indicate that applying Myristoyl Pentapeptide-17 for 14 days can lead to eyelash growth and increased eyelash density.
Indeed, whether it's eyelashes or hair, they fundamentally consist of hair, and often require similar active ingredients. Our UNILIPO MULTI-CORRECTING Eye Cream Plus encapsulates the potent ingredients mentioned above, providing you with the ultimate eyelash growth booster.
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