"PQQ is said to have antioxidant properties and activate mitochondrial regeneration? Today, let's delve into it!"
"Humanity has been searching for the fountain of youth, with the heat of stem cells and NMN not yet subsiding, a new anti-aging star emerges - Pyrroloquinoline quinone."
PQQ Benefits
PQQ is a water-soluble coenzyme, and its most well-known benefit is its antioxidative properties.
The antioxidant system consists of two types of substances. One type is oxidoreductases, such as the well-known superoxide dismutase (SOD), which can efficiently reduce the content of peroxides through catalytic action. However, enzymes are delicate and prone to deactivation.
Another type is non-enzymatic antioxidants, such as vitamin C and E.
These substances mostly cannot cycle indefinitely like enzymes; they undergo self-consumption when combating free radicals. However, they are relatively more stable and better preserved compared to enzymes.
What's unique about PQQ is that it not only serves as a coenzyme for oxidoreductases but also enhances enzyme activity by binding to the active sites of enzymes.
On the other hand, PQQ itself is also an antioxidant. Therefore, PQQ possesses a remarkably strong antioxidant capacity, and under certain experimental conditions, its antioxidant power has been found to surpass that of vitamin C and other antioxidants.
In cellular and animal studies, it has been discovered that PQQ can promote mitochondrial growth and repair, thereby enhancing cellular energy metabolism and preventing mitochondrial aging.
It can also stimulate neuronal growth, thereby promoting neuroprotection and improving cognitive function.
Additionally, because PQQ theoretically has the potential to activate the longevity protein sirtuins similar to NMN, it has gained popularity in niche circles as a newcomer in the anti-aging field.
However, as our science-savvy friends often know, theoretical effectiveness and efficacy in cell and animal experiments do not necessarily translate to the same effects in the human body.
Therefore, whether it can combat aging depends on clinical data.
Clinical Data
PQQ is a relatively new nutrient, and current clinical research is not yet sufficient.
Preliminary experiments suggest that oral PQQ supplementation can increase cerebral blood flow in the prefrontal cortex, potentially preventing cognitive decline in the elderly, particularly in attention and working memory.
In another clinical trial, it was observed that in the experimental group taking PQQ, the average low-density lipoprotein decreased from 136.1 to 127.0 mg/dL, albeit slightly.
Furthermore, some clinical trials have found that PQQ can promote sleep and reduce inflammation markers. However, due to the lack of placebo control, the evidence is relatively weak, so it is not discussed in detail.
Summarize
In summary,while PQQ shows promise, based on current research evidence, it's premature to label PQQ as the next anti-aging superstar. Whether you want to give it a try or not depends on your own choice!
Also, since there is limited safety research on this new nutrient, it's advisable for individuals in pregnancy or lactation to refrain from trying it out without proper consultation.
Comments