The slightly delayed UNILIPO Collagen Plumping Serum 2.0 is finally here! Of course, those familiar with UNILIPO products can immediately recognize it by its packaging, specifically the golden band at the bottom that signifies it's the upgraded version.
UNILIPO COLLAGEN PLUMPING SERUM 1.0 UNILIPO COLLAGEN PLUMPING SERUM 2.0
Key Active Ingredients of Version 2.0
Compared to Version 1.0, Version 2.0 has enhanced its classic "Three Musketeers" formula by adding 3% UNISOUL® Reborn (pterostilbene lipid microspheres), hydrolyzed collagen, and recombinant Type III collagen as active ingredients.
UNILIPO COLLAGEN PLUMPING SERUM | UNILIPO COLLAGEN PLUMPING SERUM 2.0（Newly Upgraded） |
2% Cellfie | 2% Cellfie |
2%ZPC®Beauty056S | 2%ZPC®Beauty056S |
2%PRO-COLL-ONE+®SP PX | 2%PRO-COLL-ONE+®SP PX |
/ | 3%UNISOUL® Reborn |
/ | 1%Hydrolyzed collagen and recombinant Type Ⅲ collagen |
You read that right, the pterostilbene lipid microspheres found in both the pterostilbene whitening essence and VA essence have been generously added to the COLLAGEN PLUMPING SERUM this time.
In the previous educational article on Version 1.0 of the COLLAGEN PLUMPING SERUM, we already introduced the benefits of the key active ingredients. Today, let's briefly review them again.
2% CELLFIE
INCI Name: [THYMUS VULGARIS (THYME) FLOWER/LEAF EXTRACT], sourced from Chemyunion in the USA.
Cellfie is a liposome-encapsulated [THYMUS VULGARIS (THYME) FLOWER/LEAF EXTRACT]. It promotes the differentiation of adipose stem cells into adipocytes and enhances lipid synthesis in adipocytes through the activation of the PPAR-γ gene.
PPAR-γ gene: Peroxisome proliferator-activated receptor gamma, a key transcription factor for adipocyte differentiation. Its activation promotes adipogenesis, increasing both the number of adipocytes and lipid storage.
Even at low concentrations, Cellfie can significantly enhance the expression of the PPAR-γ gene at the transcriptional level.
Adiponectin (ADPN) is a hormone released by subcutaneous white fat, responsible for various metabolic processes in the skin and organs. Interestingly, the activation of PPAR-γ significantly enhances the production of adiponectin, which directly helps subcutaneous fat accumulate more quickly.
How impressive are the results? Compared to the control group without induced fat, Cellfie can increase adiponectin synthesis by 2768 times. Yes, that's over 2700 times!
Cellfie can significantly enhance the synthesis of adiponectin
From cellular experiments, it's very clear that the Cellfie experimental group can significantly increase fat production labeled with red fluorescence.
In a real-life double-blind controlled trial, the results showed that 2% Cellfie can significantly reduce perioral wrinkles, crow's feet, nasolabial folds, and smile lines.
Some might worry that increasing the generation of subcutaneous fat would make the already loose and droopy face appear even bulkier. However, clinical trial findings tell us that after 60 days of consistent use, there was a visible improvement in facial contouring. Not only did the face not appear larger, but it actually looked smaller and more compact.
The principle behind Cellfie's "fat-boosting" action is quite simple. By activating genes like PPAR-γ, it increases the synthesis of adiponectin, stimulating fat production and the differentiation of fat cells, thereby redefining facial contours and making them more three-dimensional.
2% ZPC-Beauty056S
INCI Name: [ACETYL HEXAPEPTIDE-7] and others.
Though it goes by the name of a peptide, this ingredient is also a promoter of fat production. It's a bona fide breast enhancement component, affectionately nicknamed "bust peptide," as the noticeable changes in breast size after two months of use can attest to.
Firstly, it promotes the differentiation of adipocytes. The differentiation of stem cells into fat cells requires the involvement of two crucial components: a transcriptional coactivator called PGC-1α and the target gene of Cellfie, PPAR-γ.
While Cellife activates PPARγ, [ACETYL HEXAPEPTIDE-7] significantly increases the expression of the PGC-1α gene at the transcriptional level, thus acting synergistically.
Apart from promoting differentiation, it also enhances fat production. In cellular experiments, compared to undifferentiated cells, ACETYL HEXAPEPTIDE-38 increases the lipid content in fat cells by 27% to 32%. Clinical validation of breast volume enhancement was observed in 22 women aged 50-60, all of whom showed significant improvement after 56 days of use.
2% PRO-COLL-ONE+® SP PX
INCI Name: [HYDROLYZED SOY FLOUR], sourced from Silab in France.
As fat increases, it also needs a collagen network to contain it, a task accomplished by the ample addition of PRO-COLL-ONE+.
This ingredient, sourced from Silab in France, much like Chemyunion, is one of our close partners. Its efficacy is very clear – collagen production. In cellular experiments, 0.25% PRO-COLL-ONE+ increases the production of Type I collagen by 1190%!
In clinical trials, the wrinkle-fighting ability of 2% PRO-COLL-ONE+ is comparable to that of 3% Matrixyl ([PALMITOYL PENTAPEPTIDE-3]) and 0.075% [RETINOL], with even higher user satisfaction.
3% UNISOUL® Reborn (newly added in the upgraded version)
INCI Name: PTEROCARPUS MARSUPIUM BARK EXTRACT,
UNILIPO patented ingredient
Patent Application Number: 202310564303.5
Invention Name: Preparation Method and Application of a Supermolecular Pterostilbene Microcapsule for Whitening and Anti-aging
Yes, you read that right. The new upgraded version of the COLLAGEN PLUMPING SERUM also contains UNILIPO's exclusive flagship ingredient – pterostilbene lipid microsphere. However, this time it's not primarily for whitening and spot reduction but for wrinkle reduction.
Although free pterostilbene has low penetration efficiency, its ability to promote collagen production is absolutely potent. Just 0.03% of free pterostilbene can rival the collagen-producing ability of high concentrations of vitamin C. However, once encapsulated, only one-tenth of the original concentration of pterostilbene is needed (that is, 0.003% pterostilbene), which can outperform a 10% complex of vitamin C and vitamin E.
The potent anti-aging effects of pterostilbene are further demonstrated in real human clinical trials. After just one month of use, it can reduce over 50% of the number of fine lines.
Other Active Ingredients
1% Hydrolyzed Collagen + Recombinant Type III Collagen (New Addition)
The primary collagen proteins in the dermis are Type I and Type III, so adding hydrolyzed products of these two collagens inherently provides good biocompatibility, making it less likely to cause intolerance or sensitivity.
Of course, there's no need to exaggerate the efficacy of hydrolyzed collagen. They are simply collagen peptides with very low molecular weights, primarily focused on enhancing skin hydration and soothing.
Note: The recombinant Type III collagen added to the formula is recorded as [COLLAGEN] in the ingredient list.
2% SHINE+GLYCERYL GLUCOSIDE (New Addition)
[Glyceryl Glucoside] is actually added to many of our products because it not only provides strong moisturization to the skin but also significantly promotes the synthesis of aquaporin 3 (AQP3) in the skin.
Aquaporin 3 (AQP3) is a channel protein on the cell membrane that facilitates the passage of water molecules and natural moisturizing factors like glycerol. Water from the dermis is continuously transported to the epidermis through AQP3. Therefore, a [Glyceryl Glucoside] can achieve both internal and external hydration effects.
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