In the previous article, we talked about the benefits of butyric acid. Now let's return to the original question: What methods can increase butyric acid?
Since butyrate can be produced in our bodies, we can think of three methods: directly supplementing butyrate, supplementing bacteria that can produce butyrate, and consuming foods that promote the proliferation of butyrate-producing bacteria.
Directly supplementing butyrate salts
Whether in animal or human clinical settings, this is the fastest and most direct method. Butyrate salts or butyrate glycerides are the most readily available raw materials for this purpose.
Tesseract Medical Research
ProButyrate™
Designs for Health
Tri-Butyrin Supreme
Of course, it's important to note that in clinical interventions for weight loss, the dosage of butyrate salt oral supplements is typically quite high. If we calculate it based on body weight, the daily intake should be around 20 mg/kg. For instance, for an adult woman weighing 60 kg, this would amount to consuming 1.2 g of butyrate salt per day.
While the recommended daily dosage in health supplements can help restore intestinal barrier function, improve gut microbiota structure, and alleviate issues like diarrhea and enteritis, relying solely on it for weight loss might be less effective.
However, there's no need to despair. The good news is that we conducted a series of experiments last year. Even with moderate to low doses of butyrate compounds, ranging from 100-200 mg per day, combined with other ingredients that can reduce insulin resistance and activate brown adipose tissue thermogenesis, we achieved remarkably powerful weight loss and waist-slimming effects.
For instance, as mentioned earlier, using butyrate salts alone reduced waist circumference by around 5 cm over 6 months. However, many individuals we tested experienced reductions of over 5 cm within just one month.
Supplementing probiotic bacteria that produce butyrate
Previous research has also consistently shown that consuming probiotic bacteria capable of producing butyrate can reduce weight, improve glucose tolerance and insulin resistance, and mitigate liver fat accumulation and damage in experimental animals under high-fat diet conditions.
The key lies in which bacteria can produce butyrate in large quantities. Many bacteria within the Firmicutes phylum in the gut are prolific producers of butyrate. For example, species within the Ruminococcaceae family, such as Faecalibacterium prausnitzii, and particularly species within the Bacillaceae family, such as Clostridium butyricum.
While formulations of Faecalibacterium prausnitzii are not readily available, Clostridium butyricum can be more easily purchased online from pharmacies or hospitals.
Of course, in many common probiotic supplements like Bifidobacterium or Lactobacillus, most strains don't directly produce butyrate. Does this mean they won't produce butyrate at all? Not at all. Numerous clinical studies have shown that the intake of probiotics like Bifidobacterium and Lactobacillus can also promote the proliferation of bacteria within the Firmicutes phylum in the gut, indirectly increasing the level of butyrate in the body.
So, there's no need to worry that the probiotics you're taking aren't effective. Every effort counts toward the harvest.
Supplementing specific foods and prebiotics
No matter how good or fast the methods are, optimizing the types and quantities of food intake to enhance the production of butyrate salts is undoubtedly the safest and most effective approach.
Any food containing ample dietary fiber, including but not limited to grains, nuts, legumes, fruits, and vegetables, is essential for probiotics every day. By metabolizing these dietary fibers, certain bacterial strains can produce corresponding butyrate.
Note:
If your daily dietary habits consist of high protein and high fat, with a low intake of dietary fiber, not only will it greatly affect the generation of new butyrate, but it will also lead to decreasing levels of butyrate in the body.
If you're unable to consume a lot of fruits and vegetables in your daily diet, consider supplementing with some prebiotics. Glucans, inulin, and oligofructose are all favorite foods of butyrate-producing bacteria.
UNILIPO YEAST β-GLUCAN
Jarrow prebiotic inulin-FOS
Finally, here are some terms you should understand
GLP-1 (Glucagon-like peptide-1): GLP-1 is a peptide hormone composed of 30 amino acids. Its main function is to stimulate insulin secretion and inhibit glucagon secretion. Currently, the most successful antidiabetic and weight loss drugs, such as semaglutide and liraglutide, are developed based on the principle of GLP-1.
HOMA-IR (Homeostasis Model Assessment of Insulin Resistance): HOMA-IR is an index of insulin resistance. A higher HOMA-IR indicates poorer pancreatic function, while a lower value suggests better pancreatic function.
Ghrelin: Ghrelin, also known as the hunger hormone or growth hormone secretagogue, is a 28-amino acid peptide. Ghrelin stimulates the release of growth hormone from the pituitary gland and is a key signal factor for generating appetite and hunger. It is one of the most important physiological bases for human hunger.
Ghrelin is considered the most typical "obesity signal bullet". Selectively blocking the ghrelin signaling pathway can significantly reduce food intake and decrease body fat.
White Adipose Tissue (WAT) and Brown Adipose Tissue (BAT): There are two types of adipose tissue in mammals. White adipose tissue (WAT) stores triglycerides as reserve energy, mainly under the skin and around internal organs. Brown adipose tissue (BAT) contains mitochondria and appears brown. The function of BAT is to generate heat by burning energy. Adult humans have relatively little brown adipose tissue, mainly distributed around the neck, chest, and spine.
White adipose tissue can be converted into brown adipose tissue and is regulated by various factors, including hormones (such as insulin, glucocorticoids, and thyroid hormones), environmental temperature, and activity levels.
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